Weekend Effect and Mortality Outcomes in Aortic Dissection: A Prospective Analysis

Cosmin Marian Banceu¹, Marius Harpa², Klara Brinzaniuc², Nicolae Neagu², Dan Alexandru Szabo², Diana Mariana Banceu³, Hussam Al Hussein², Daiana Cristutiu³, Alexandra Puscas², Alexandru Stan², Marvin Oprean⁴, Adrian Popentiu⁵, Marius Neamtu Halic⁶, Horatiu Suciu²

1 Doctoral School, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania
2 George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania.
3 Emergency Institute for Cardiovascular Diseases and Transplantation Targu Mures, Romania; Targu Mures Institute for Cardiovascular Diseases and Heart Transplantation, Targu Mures, Romania
4 Amherst College, Amherst, Massachusetts, USA
5 Faculty of Medicine, Lucian Blaga University of Sibiu, Sibiu, Romania
6 Swiss Federal Institute of Forest, Snow and Landscape Research WSL, Birmensdorf, Switzerland; Institute of Environmental Engineering, ETH Zurich, Switzerland; Swiss Federal Institute for Environmental Science and Technology – Eawag, Switzerland

DOI: 10.2478jccm-2024-0014

Background: Aortic dissection (AD) is a critical heart condition with potentially severe outcomes. Our study aimed to investigate the existence of a “weekend effect” in AD by examining the correlation between patient outcomes and whether their treatment occurred on weekdays versus weekends.
Methods: Specifically, we prospectively analysed the effect of weekday and weekend treatment on acute AD patient outcomes, both before surgical intervention and during hospitalization, for 124 patients treated from 2019–2021, as well as during 6 months of follow-up.
Results: The mean age of the study population was 62.5 years, and patient age exhibited a high degree of variability. We recorded a mortality rate before surgery of 8.65% for the weekend group and 15% for the weekday group, but this difference was not statistically significant. During hospitalization, mortality was 50% in the weekend group and 25% in the weekday group, but this difference was not statistically significant. Discharge mortality was 9.61% in the weekend group and 5% in the weekday group.
Conclusions: Our findings suggest that there was no significant difference in mortality rates between patients admitted to the hospital on weekends versus weekdays. Therefore, the period of the week when a patient presents to the hospital with AD appears not to affect their mortality.